Drug Discovery

Case Number

Title

Non-Confidential Summary

Issued Patent Lead Inventor's Info
BAS_REN.005 Cell Lines which Constitutively Express IGF-1 and IGF-1 R  
BEN_JEF.003 Compositions And Methods For Modulating The Activity Of G Protein-Kinases US Patent No. 6,255,069 Link
CHA_TUN.004

Kinase Assay that can Detect ATP Hyperphosphorylation

NCS for CHA_TUN 004

   
CHU_MON.001 Fibulin-2 Null Mutant Mice   Link
CRO_CAR.002

Compositions, Kits and Methods Relating to the Human FEZ1 Gene, a Novel Tumor Suppressor Gene

NCS for Croce tumor suppressor techs (CRO_CAR.002,004,005,016)

US Patent No. 7,141,417
US Patent No. 7,777,005
 
CRO_CAR.004

The Human FHIT Gene

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

US Patent No. 7,220,834
US Patent No. 6,774,217
US Patent No. 6,242,212
US Patent No. 5,928,884
 
CRO_CAR.009

TCL-1 Gene And Protein And Related Methods And Compositions

NCS for Croce TCL-1 techs (CRO_CAR.009, 015)

US Patent No. 5,985,598
US Patent No. 7,175,995
US Patent No. 7,749,715
 
CRO_CAR.015

Human Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted TCL1 Expression

NCS for Croce TCL-1 techs (CRO_CAR.009,015)

US Patent No. 7,728,189
US Patent No. 8,168,854
 
CRO_CAR.016

Novel Tumor Suppressor Gene and Compositions and Methods for Making and Using the Same

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

   
CRO_CAR.017

Role of microRNA Genes In Human Cancer

NCS for Croce miRNA techs (CRO 17, 25)

US Patent No. 7,723,035
US Patent App 12/319,331
US Patent App 12/727,778
 
CRO_CAR.019 Involvement Of The ALL-1 Gene In A Solid Tumor1 US Patent No. 5,567,586  
CRO_CAR.025

microRNA genes in cancer diagnosis and treatment

NCS for Croce miRNA techs (CRO 17, 25)

US Patent No. 7,723,030
US Patent App 12/751,463
US Patent App 12/767,279
 
HOU_YAM.005 Apoptosis of Cardiomyocytes   Link
HOU_YAM.006 Antibiotics Targeting a Growth-Dependent Bacterial Enzyme   Link
IAC_LOR.001

A Human Model System For In Vitro Development Of The Dopaminergic Phenotype

NCS for IAC_LOR.001

US Patent No. 7,195,910 Link
IOZ_REN.001 A Role For Decorin In Tumor Suppression US Patent No. 6,524,573 Link
KOP_HIL.006 Polypeptides Fused with Alfalfa Mosaic Virus or Ilarvirus Capsid Proteins US Patent No. 6,042,832
US Patent No. 6,448,070
 
MAH_MYG.001 Anti-Desmoglein 1-B Antibodies    
NEV_MAR.001

Establishment of a New Human Androgen-Dependent Prostate Cancer Cell Line that is Tumorigenic in Nude Mice

NCS for NEV_MAR.001

  Link
OSH_MIC.001 Chronic Recurring Migraine Headache Model in Rodents   Link
OSH_MIC.002 Inherited Rat Headache Model   Link
PASC_JOH.001 Crystal Structure of the Active Conformation of PARP-1 and Novel Binding Pockets for Inhibitor Design   Link
RAB_JOS.001

Development of an Enhancer/Promoter Pair for Heart Selective Gene Expression

NCS for RAB_JOS.001

   
THO_JEF.001 Nitric Oxide Donor Compositions, Methods, Apparatus, and Kits for Alleviating Vasoconstriction and Vasospasm in a Mammal US Patent No. 6,358,536  
WIL_KEV.001 Human Genomic Clone Encoding Human Chondroitin 6-Sulfotransferase US Patent No. 6,399,358