Therapeutics

Case Number

Title

Non-Confidential Summary

Issued Patent Lead Inventor's Info
BER_ERI.001 Use of Tempol in the Prevention of Photoaging US Patent No. 5,840,734  
BRA_PAU.001

Novel drug to inhibit human platelet aggregation

NCS for BRA_PAU.001

   
CRO_CAR.002

Compositions, Kits and Methods Relating to the Human FEZ1 Gene, a Novel Tumor Suppressor Gene

NCS for Croce tumor suppressor techs (CRO_CAR.002, 004, 005, 016)

US Patent No. 7,141,417
US Patent No. 7,777,005
 
CRO_CAR.004

The Human FHIT Gene

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

US Patent No. 7,220,834
US Patent No. 6,774,217
US Patent No. 6,242,212
US Patent No. 5,928,884
 
CRO_CAR.009

TCL-1 Gene And Protein And Related Methods And Compositions

NCS for Croce TCL-1 techs (CRO_CAR.009, 015)

US Patent No. 5,985,598
US Patent No. 7,175,995
US Patent No. 7,749,715
 
CRO_CAR.015

Human Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted TCL1 Expression

NCS for Croce TCL-1 techs (CRO_CAR.009,015)

US Patent No. 7,728,189
US Patent No. 8,168,854
 
CRO_CAR.016

Novel Tumor Suppressor Gene and Compositions and Methods for Making and Using the Same

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

   
CRO_CAR.017

Role of microRNA Genes In Human Cancer

NCS for Croce miRNA techs (CRO 17, 25)

US Patent No. 7,723,035
US Patent App 12/319,331
US Patent App 12/727,778
 
CRO_CAR.019 Involvement Of The ALL-1 Gene In A Solid Tumor1 US Patent No. 5,567,586  
CRO_CAR.025

microRNA genes in cancer diagnosis and treatment

NCS for Croce miRNA techs (CRO 17, 25)

US Patent N.o 7,723,030 US Patent App
12/751,463
US Patent App 12/767,279
 
DIE_BER.010 Recombinant Rabies for Pre- and Post-Exposure Prophylaxis   Link
DIE_BER.012

A Method to Modulate and Enhance the Immune Response through Prime/Boost Immunization

NCS for DIE_BER.012

  Link
DIE_BER.013

Rabies TriGAS in a combination vaccine

NCS for DIE_BER.013

   
DUR_MAT.005

Insulin And Insulin-Associated Peptides For Cerebral Health

NCS for DUR_MAT.005

   
FER_AND.002

Antibody-based Inhibitors of Excessive Deposition of Fibrotic Tissue

NCS for FER_AND.002

  Link
HOU_YAM.005 Apoptosis of Cardiomyocytes   Link
IOZ_REN.001 A Role For Decorin In Tumor Suppression US Patent No. 6,524,573 Link
KAS_DAV.001

A Small Bowel Purgative for Wireless Capsule Endoscopy

NCS for KAS_DAV.001

   
KOP_HIL.006 Polypeptides Fused with Alfalfa Mosaic Virus or Ilarvirus Capsid Proteins US Patent No. 6,042,832
US Patent No. 6,448,070
 
MEN_SUE.002

Cell Migration Leading to Posterior Capsule Opacification can be Prevented by Inhibition of Src Kinase Activities

NCS for MEN_SUE.002

US Patent Appl. 11/913,798  
NEV_MAR.005/ NJA_VIN.002/ NJA_VIN.005

Treatment of Prostate Cancer

NCS for NEV_MAR.005, NJA_VIN.002, NJA_VIN.005

   
RAB_JOS.001

Development of an Enhancer/Promoter Pair for Heart Selective Gene Expression

NCS for RAB_JOS.001

   
SAN_JAM.001

Peptides with High Affinity for Heparin and for Proteoglycans to be used to Promote Endothelialization of Synthetic Vascular Graft Surfaces, or to Target the Delivery of Drugs to Cell Surfaces

NCS for SAN_JAM.001, .002

US Patent No. 6,855,801  
SAN_JAM.002

Peptides that Neutralize Heparin or Proteoglycans, or Promote Cell Adhesion or Drug Delivery

NCS for SAN_JAM.001, .002

US Patent No. 7,259,140  
SCH_JAY.001

Treatment of Parkinson's Disease with Oligonucleotide and Triplex Technology

NCS for SCH_JAY.001, 002, 004, 008

  Link
SCH_JAY.002

Partial Agonists at the Glycine Modulatory Site of the NMDA Receptor for Treating Cognitive Dysfunction in Parkinson's Disease

NCS for SCH_JAY.001, 002, 004, 008

  Link
SCH_JAY.004

Method of Treating Parkinson's Disease and Composition for the Same

NCS for SCH_JAY.001, 002, 004, 008

US Patent No. 7,160,913 Link
SCH_JAY.008

Treatment of Parkinson's Disease and Parkinson's Disease Treatment-related Complications with RNA Inhibition Therapies

NCS for SCH_JAY.001, 002, 004, 008

  Link
SHO_SUN.001

Pure Protein Nanoparticles for Drug Delivery

NCS for SHO_SUN.001

   
STR_DAV.001 SV40 Viral Vectors for Targeted Integration Into Cells US Patent No. 5,863,794 Link
SUN_XIA.001 Implantable Sensor and System for Measurement and Control of Blood Constituent Levels US Patent No. 5,995,860
US Patent No. 6,122,536
 
THO_JEF.001 Nitric Oxide Donor Compositions, Methods, Apparatus, and Kits for Alleviating Vasoconstriction and Vasospasm in a Mammal US Patent No. 6,358,536  
TRO_DAV.001

Increase bioavailability and efficacy of ALS-treating pharmacological compounds

NCS for TRO_DAV.001

   
WAL_PAU.010

Microwave Balloon Catheter

NCS for WAL_PAU.010

   
WIC_ERI.010

Competitive Inhibition of miRNAs

NCS for WIC_ERI.010

   
WIL_JOH.005 Design and Development of Masked Therapeutic Antibodies to Limit Off-Target Effects: Application to Anti-EGFR Antibodies (Also known as "EGFR-Specific ScFvs Engineered to Enable Selective Antigen Recognition Upon Proteolytic Activation")    
ZAL_AND.002 Inhibition of Extracellular Matrix Synthesis By Antisense Compounds Directed to Nuclear Proto-Oncogenes US Patent No. 6,133,242