Drug Discovery

Case Number


Non-Confidential Summary
Issued Patent Lead Inventor's Info
BAS_REN.005 Cell Lines which Constitutively Express IGF-1 and IGF-1 R    
BEN_JEF.003 Compositions And Methods For Modulating The Activity Of G Protein-Kinases US Patent No. 6,255,069 Link

Kinase Assay that can Detect ATP Hyperphosphorylation

NCS for CHA_TUN 004

CHU_MON.001 Fibulin-2 Null Mutant Mice   Link

Compositions, Kits and Methods Relating to the Human FEZ1 Gene, a Novel Tumor Suppressor Gene

NCS for Croce tumor suppressor techs (CRO_CAR.002,004,005,016)

US Patent No. 7,141,417
US Patent No. 7,777,005

The Human FHIT Gene

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)

US Patent No. 7,220,834
US Patent No. 6,774,217
US Patent No. 6,242,212
US Patent No. 5,928,884

TCL-1 Gene And Protein And Related Methods And Compositions

NCS for Croce TCL-1 techs (CRO_CAR.009, 015)

US Patent No. 5,985,598
US Patent No. 7,175,995
US Patent No. 7,749,715

Human Chronic Lymphocytic Leukemia Modeled in Mouse by Targeted TCL1 Expression

NCS for Croce TCL-1 techs (CRO_CAR.009,015)

US Patent No. 7,728,189
US Patent No. 8,168,854

Novel Tumor Suppressor Gene and Compositions and Methods for Making and Using the Same

NCS for Croce tumor suppressor techs (CRO 2,4,5,16)


Role of microRNA Genes In Human Cancer

NCS for Croce miRNA techs (CRO 17, 25)

US Patent No. 7,723,035
US Patent App 12/319,331
US Patent App 12/727,778
CRO_CAR.019 Involvement Of The ALL-1 Gene In A Solid Tumor1 US Patent No. 5,567,586  

microRNA genes in cancer diagnosis and treatment

NCS for Croce miRNA techs (CRO 17, 25)

US Patent No. 7,723,030
US Patent App 12/751,463
US Patent App 12/767,279
HOU_YAM.005 Apoptosis of Cardiomyocytes   Link
HOU_YAM.006 Antibiotics Targeting a Growth-Dependent Bacterial Enzyme   Link

A Human Model System For In Vitro Development Of The Dopaminergic Phenotype

NCS for IAC_LOR.001

US Patent No. 7,195,910 Link
IOZ_REN.001 A Role For Decorin In Tumor Suppression US Patent No. 6,524,573 Link
KOP_HIL.006 Polypeptides Fused with Alfalfa Mosaic Virus or Ilarvirus Capsid Proteins US Patent No. 6,042,832
US Patent No. 6,448,070
MAH_MYG.001 Anti-Desmoglein 1-B Antibodies    

Establishment of a New Human Androgen-Dependent Prostate Cancer Cell Line that is Tumorigenic in Nude Mice

NCS for NEV_MAR.001

OSH_MIC.001 Chronic Recurring Migraine Headache Model in Rodents   Link
OSH_MIC.002 Inherited Rat Headache Model   Link
PASC_JOH.001 Crystal Structure of the Active Conformation of PARP-1 and Novel Binding Pockets for Inhibitor Design   Link

Development of an Enhancer/Promoter Pair for Heart Selective Gene Expression

NCS for RAB_JOS.001

THO_JEF.001 Nitric Oxide Donor Compositions, Methods, Apparatus, and Kits for Alleviating Vasoconstriction and Vasospasm in a Mammal US Patent No. 6,358,536  
WIL_KEV.001 Human Genomic Clone Encoding Human Chondroitin 6-Sulfotransferase US Patent No. 6,399,358